Successful Treatment of a Child With Extensively Drug-Resistant Tuberculous Meningitis.
نویسندگان
چکیده
Unlike in pulmonary multidrug-resistant (MDR) tuberculosis, the clinical outcome of MDR tuberculous meningitis (TBM) in children, including extensively drug-resistant tuberculosis, is poor and management is challenging. We report the successful treatment of a case of extensively drug-resistant TBM in a 4-year-old girl, and we discuss implications for tuberculosis diagnosis and chemotherapy.
منابع مشابه
Description of primary multidrug-resistant tuberculous meningitis in an Italian child.
Tuberculous meningitis is the most severe form of tuberculosis and causes substantial morbidity and mortality in adults and children. The prevalence of multidrug-resistant (rifampin-isoniazid) strains requires the use of more toxic second-line drugs. We report a case of tuberculous meningitis in a 3-year-old Italian child.
متن کاملمننژیت سلی در شیرخوار زیر 3 ماه؛ گزارش مورد و مرور مقالات
Tuberculosis especially tuberculous meningitis rarely accurs before 3 months of age. Though treatable, it may be fatal despite modern treatment. The diagnosis of congenital TB/TB meningitis should be considered in any neonate/infant with pneumonia –meningitis who fails to respond to conventional treatment, particularly in a child from ethnic or socioeconomic environment where tuberculosis is ...
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Tuberculous meningitis continues to be a serious problem for physicians because it is difficult to make an early diagnosis and the consequences of delaying treatment are severe. The objective of this study is to provide data for the optimization of diagnostic and timely treatment of tuberculous meningitis. Of the 401 human immunodeficiency virus (HIV)-negative tuberculous meningitis patients in...
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Toxic manifestations during isoniazid therapy are encountered in less than 5% of cases treated, and we have been able to trace little mention of them in children in the literature. The drug is now widely used in the treatment of tuberculosis and is universally prescribed as an adjuvant to streptomycin in tuberculous meningitis. The following case report concerns a child who developed pellagra l...
متن کاملمقایسه غلظت آدنوزین‌دآمیناز مایع مغزی‌نخاعی در بیماران مننژیت سلی و غیر سلی
Background and Aim: Diagnosis of tuberculous meningitis is difficult because of its non-specific clinical presentations which may be confused with other disorders of central nervous system. The initiation of anti-TB medication can often be delayed because of lack of available laboratory tests. This study was aimed at evaluating the adenosine deaminase (ADA) concentration in differentiating tube...
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ورودعنوان ژورنال:
- Journal of the Pediatric Infectious Diseases Society
دوره 4 3 شماره
صفحات -
تاریخ انتشار 2015